Pregnancy loss can take an enormous emotional toll on individuals and couples attempting to build a family.
At Anmol Fertility and IVF centre our goal is to help you to understand there is a biological reason behind miscarriage- and that most women go on to successfully conceive via the help of our innovative technologies .
It may be surprising to hear , but miscarriage is a common event. Much of the time these events occur so early in the conception process that a woman may not even know she was pregnant. These early losses can sometimes be documented through some blood tests ( chemical pregnancy )
On a positive note , one or even two miscarriage does not mean that the woman will not be able to have a baby . Pregnancy after miscarriages are very common .We can help .
A miscarriage is a spontaneous loss of pregnancy before 20 weeks of gestation . Recurrent miscarriage is when the miscarriage occurs more than once consecutively .
We have a team of fertility specialists who specialise in the diagnosis and treatment of miscarriage .
We offer cutting edge PGS Embryo testing that predicts chromosomal abnormalities .
We offer Counselling sessions for those who experience a pregnancy loss.
In many a cases pregnancy stops growing because there is a genetic issue within the embryo itself.
An imbalance in the number of chromosomes (aneuploidy) will often result in miscarriage.
Causes of miscarriage:
Genetic : 50 to 60 percent of all first trimester losses are caused by chromosomal abnormalities on part of the mother or father or both.
Age: Older women are more likely to have eggs with chromosomal irregularities and so age is a common reason for miscarriage .
Anatomical abnormalities : Septum in the uterus , fibroids , polyps are also associated with miscarriage. They may be surgically removed .
Cervical incompetence is a cause of sudden relatively painless 2 nd trimester pregnancy loss and can be treated in the subsequent pregnancy with a cerclage.
Immunological factors:Placental insufficiency and miscarriage can result from abnormal blood clotting. Common causes of abnormal blood clotting are Antiphospholipid antibody (APLA )syndrome or Lupus anticoagulant .
Thromophilias are a group of disorders that promote blood clotting . The major gene mutations that lead to inherited thrombophilias are factor V Leiden , protein C and S deficiency , antithrombin III deficiency , MTHFR C677T gene mutation leading to hyperbomocysteinemia, LAC , ACLA .
A combination of low dose aspirin and low molecular weight heparin gives excellent chance of a successful outcome .
Endocrine problems : Thyroid and pituitary hormone imbalance is a cause of miscarriage .
Treatment – depends result of fertility evaluation .
Hormonal treatment , surgical treatment depending on the cause.
If all tests including chromosomal problems are ruled out , then we may recommend you to attempt pregnancy after a gap of about 2 to 3 months.
PGS and IVF
Aneuploidy (incorrect number of chromosomes) is a common genetic cause of miscarriage.
PGS – preimplantation genetic screening allows for genetic analysis of embryos prior to IVF and may increase the odds of a healthy pregnancy and childbirth and reduce the chance of miscarriage by allowing Embryologist’s to implant only healthy , chromosomally normal embryos.